Rare Presentation of Aggressive B-Cell Lymphoma as Ileocolic Intussusception in a Young Adult: A Case Report

GUETMY Zakaria

UM5 Université Mohamed V Rabat, Morocco.

Aragon Othman

UM5 Université Mohamed V Rabat, Morocco.

KAID Mohamed Kaid *

UM5 Université Mohamed V Rabat, Morocco.

Dato Outban

UM5 Université Mohamed V Rabat, Morocco.

Othman Alaoui

UM5 Université Mohamed V Rabat, Morocco.

Moctar Noufou

UM5 Université Mohamed V Rabat, Morocco.

Yahya Khedid

UM5 Université Mohamed V Rabat, Morocco.

*Author to whom correspondence should be addressed.


Abstract

Intussusception is defined as the telescoping of a segment of the gastrointestinal tract into an adjacent one. Adult intussusception, a rare yet critical gastrointestinal occurrence, accounts for 5% of all intussusceptions. Primary gastro-intestinal lymphoma accounts for 1–4% of all gastro-intestinal malignancies. 90% of them have B-cell non-Hodgkin lymphoma (NHL). The most prevalent lymphoma producing intussusception is diffuse large B-cell lymphoma.

We report a case of a 21-year-old male with acute ileocolic intussusception who was ultimately diagnosed with aggressive B-cell lymphoma. Computed tomography showed ileo-colic intussusception. A right hemicolectomy was performed, with ileotransverse anastomosis  was done with post-operative chemotherapy.

This case illustrates the rare occurrence of intussusception secondary to lymphoma in adults. We emphasize the importance of including diffuse large B-cell lymphoma in the differential diagnosis of adult ileocolic intussusception to ensure accurate diagnosis and appropriate management.

Keywords: Ileocolic intussusception, large B-cell lymphoma, primary gastro-intestinal lymphoma, intestinal obstruction


How to Cite

Zakaria, GUETMY, Aragon Othman, KAID Mohamed Kaid, Dato Outban, Othman Alaoui, Moctar Noufou, and Yahya Khedid. 2025. “Rare Presentation of Aggressive B-Cell Lymphoma As Ileocolic Intussusception in a Young Adult: A Case Report”. Asian Journal of Research in Surgery 8 (2):491-97. https://doi.org/10.9734/ajrs/2025/v8i2324.

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