Unusual Location of Synovial Sarcoma of the Abdominal Wall: About a Case and Review of the Literature
Published: 2024-06-15
Page: 144-149
Issue: 2024 - Volume 7 [Issue 2]
Mohammed Dady *
Visceral Surgery Department II, Mohammed V Military Training Hospital, Rabat, Morocco.
Imad Laamri
Visceral Surgery Department II, Mohammed V Military Training Hospital, Rabat, Morocco.
Younes EL Allami
Visceral Surgery Department II, Mohammed V Military Training Hospital, Rabat, Morocco.
Yousra Ouhamou
Visceral Surgery Department II, Mohammed V Military Training Hospital, Rabat, Morocco.
Sanae Lakhdar
Visceral Surgery Department II, Mohammed V Military Training Hospital, Rabat, Morocco.
Abderrahman EL Hjouji
Visceral Surgery Department II, Mohammed V Military Training Hospital, Rabat, Morocco.
Abdelmounaim Ait Ali
Visceral Surgery Department II, Mohammed V Military Training Hospital, Rabat, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Synovial sarcoma is a primary malignant mesenchymal tumor first described in 1893, which accounts for 2.5 – 10.5% of all primary soft tissue cancers.
Abdominal synovialosarcoma is a rare and aggressive tumor that presents diagnostic and treatment challenges, as well as a difficult to predict prognosis. In this work we present the case of a 38-year-old patient who underwent surgery due to a cystic tumor of the left anterior abdominal wall. Medical imaging, particularly abdominal CT, revealed tissue heterogeneity which leads to compression of the rectus abdominis muscle as well as the left external oblique muscle. A large single-piece surgical resection of the tumor was performed on the patient. A biphasic synovialosarcoma of the abdominal wall was confirmed by pathological examination.
Adjuvant chemotherapy was administered to the patient and after approximately 2 years he developed a recurrence of his disease which required appropriate management. It is important to discuss synovialosarcoma of the abdominal wall because of its rarity and the nonspecificity of its clinical symptoms. Its precise cause remains unknown; However, some studies suggest that particular genetic mutations may contribute to the development of this tumor. Its therapy is mainly based on surgery with adjuvant chemotherapy and/or radiotherapy which can improve the prognosis.
Keywords: Synovialosarcoma, abdominal wall, surgery, chemotherapy, radiotherapy
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References
Murphey MD, Gibson MS, Jennings BT, Crespo-Rodríguez AM, Fanburg-Smith J, Gajewski DA. Imaging of synovial sarcoma with radiologic-pathologic correlation. Radiographics. 2006;26(5): 1543–1565.
Professor Mustapha Mahfoud. Bone cancer and malignant tumors of the limbs; 2009.
Russel W, Cohen J, Enzinger et Al. A clinical and pathological staging system for soft tissue sarcomas, cancer.1977; 40:1562-1570.
Shaad, Shaikh Mohd, Mehta Keshavi, Lambe Atiya, Rajesh B. Yadav. A case report on primary renal synovial sarcoma. Asian Journal of Case Reports in Surgery. 2023;6(1):252-55.Available:https://journalajcrs.com/index.php/AJCRS/article/view/412.
Kodzo-Grey Venyo, Anthony. Primary synovial sarcoma of the prostate gland: A review of the literature. Journal of Cancer and Tumor International. 2015;3(1):1-21.Available:https://doi.org/10.9734/JCTI/2016/19541
Wang YJ, Wen SC, Chien ST, Sheu JW, Hsuea CW, Feng NH. Primary intra-abdominal synovial sarcoma. Journal of the Chinese Medical Association. 2006 Oct 1;69(10):492-5.
Karakousis CP, Blumenson LE, Canavese G, Rao U. Surgery for disseminated abdominal sarcoma. The American journal of surgery. 1992 Jun 1;163(6):560-4.
Gherlinzonif, Piccip, DE Cristofaro R, et al. Late result of a randomized trial for the treatment of soft tissue sarcomas (STS) of the extremities in adult patients (abstract). Proc ASCO. 1993;12.
Khaladkar SM, Waghmode AM, Synovial sarcoma of anterior abdominal wall, Indian J. Med. Paediatr. Oncol. March 2020;41(02):269 272.DOI: 10.4103/ijmpo.ijmpo_143_18
Deshmukh R, Mankin HJ, Singer S. Synovial sarcoma: The importance of size and location for survival. Clin Orthop Relat Res. 2004;419:155–161.
Surgical Clinic C, Mohamed V University, Rabat, Morocco. et al. “Intra-abdominal synovialosarcoma about a case and review of the literature”, Int. J.Adv. Res. 2021;9(08):89 95. août,DOI: 10.21474/IJAR01/13234
Stojadinovic A, Hoos A, Karpoff HM, et al. Soft tissue sarcomas of the abdominal wall; analysis of disease patterns and treatment. Arch Surg. 2001;136: 70–7.
Singer S, Corson JM, Demetri GD, et al. Prognostic factors predictive for survival of truncal and retroperitoneal soft tissue sarcoma. Ann Surg. 1995;221:185–195.
Antognoni P; Cerizzal; Vavassori V, et al: Postoperative radiation therapy for adult soft tissue sarcomas: A retrospective study. Ann Oncol. 1992;3;103-106.
Gherlinzonif, Piccip, De Cristofaro R et al. Late result of a randomized trial for the treatment of soft tissue sarcomas (STS) of the extremities in adult patients (abstract). Proc ASCO. 1993;12.
Mibles G, Kamtor H, laharie P, lagarde: Adjuvant radiotherapy for soft tissue sarcomas of the limbs-cancer/Radiotherapy. 2005;9.
Antognoni P, Cerizzal, Vavassori V, et al.: Postoperative radiation therapy for adult soft tissue sarcomas: A retrospective study. Ann Oncol. 1992;3: 103-106.95.
Ashby A, Ago CT, Harmer CL. Hypo fractionated radiotherapy for sarcomas. Int J Radiate Oncol Bio Phys. 1986;12: 13-17.