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Ulnar nerve compression in the Guyon’s canal is in most cases secondary to repeated trauma, fracture of the hamate or a thrombosis or arterial aneurism of the ulnar artery. Tumoral etiologies such as a compression by a lipoma or a ganglion cyst are uncommon.
The development of a ganglion cyst in the Guyon’s canal as a possible cause of ulnar nerve entrapment needs to be considered in the case of a sudden onset of hand grip weakness.
We believe that an early surgical decompression by removing the ganglion is essential for a full recovery.